Inter boss Antonio Conte is expected to name a full-strength team for the clash against Crotone, as Serie A resumes after the Christmas break.
With their early exit from the Champions League, the pressure is now on Conte to deliver the Scudetto this season.
They currently sit second in the table, behind city rivals Milan.
Conte is expected to name his best starting XI for the clash against the southern minnows.
Stefan De Vrij, Alessandro Bastoni and Milan Skrinriar will occupy the back three.
In midfield, Conte is expected to start Chilean Arturo Vidal, Nicolo Barella and Marcelo Brozovic in the central berths. Ashley Young and Achraf Hakimi will play in the wing-back positions.
Stefano Sensi and Christian Eriksen could come off the bench, should Inter find life difficult against Crotone.
This could well be one of Eriksen's last appearances for Inter in what has been a miserable year in Milan. The Dane has been heavily linked with a move to PSG, and the club have publicly stated they expect him to move on this month.
In attack, Inter will start with Romelu Lukaku and Lautaro Martinez. The pair of them notched 17 goals in Serie A in the first half of the season, and they will be expected to carry the burden for the remainder of the season.
Alex Sanchez could also make an appearance as a replacement for either man, should Crotone prove stubborn at San Siro.