Goals from Henrikh Mkhitaryan and Pedro secured a 2-0 win in the final Derby della Capitale of the season, which ended Lazio's slim hopes of qualifying for the Champions League next season.
Dzeko didn't score, but he led the line in the way all good strikers do and provided the opening goal for Henrikh Mkhitaryan. The 35-year-old soaked up a lot of pressure, and allowed attacking midfielders such as Mkhitaryan and Lorenzo Pellegrini to run into the space that Dzeko opened up.
Dzeko's technique, a facet often overlooked in his game, was vital in giving his side an outlet and a control in the game, especially in the second half.
It may be his last Rome derby, and he's going out with his head held high.
In-coming Roma boss Jose Mourinho will surely have been impressed by what he saw from the young defender in the derby, and will likely look to build his defence around the No.23 next season.
Mkhitaryan, as he so often has been this season, was in the right place at the right time, to give the Giallorossi the lead, as he latched on to Dzeko's assist.
Mkhitaryan was always an outlet, running the channels and opening space for his teammates.
This could, like Dzeko, be his final Rome derby, with he and Mourinho not getting along during their time at Manchester United together.
The Armenian is a firm fan favourite in the Italian capital, and his display this evening will only go further in solidifying his status with the Roma faithful.