Cristiano Ronaldo is expected to be put straight into the starting XI to make his second Manchester United debut against Newcastle in the Premier League.
The Portuguese superstar completed a sensational return to the Red Devils near the end of the transfer window after informing Juventus of his desire to leave Turin.
Manchester City actually emerged as a potential destination, but once Man Utd discovered Ronaldo was keen on a move back to England, they acted swiftly to ensure his return.
Ole Gunnar Solskjaer has typically been wary of firing new signings straight into the first team, instead opting to gradually introduce them into things, like he has done with Jadon Sancho.
However, Ronaldo is fit and raring to go and really hasn't featured on the bench in his entire career very much. So, he should come in as the starting centre-forward.
Sancho missed England duty due to a slight injury but he is available too, and could be positioned on the left of the attacking midfield three, with Bruno Fernandes in the middle and Mason Greenwood on the left.
Marcus Rashford is still out after recovering from shoulder surgery, while Edinson Cavani and Anthony Martial could make an appearance from the bench.
Fred is unavailable due to his ban from FIFA for turning up for international duty with Brazil without authorisation from his club.
With Scott McTominay also still on the sidelines, though getting close to a return, expect a central midfield tandem of Paul Pogba and Nemanja Matic.
The defence will be Aaron Wan-Bissaka, Raphael Varane, Harry Maguire and Luke Shaw, with David de Gea keeping his place in goal.