Chelsea manager Thomas Tuchel has a number of injury problems heading into the Premier League showdown with Liverpool on Sunday.
During the week, the Blues drew 1-1 with Brighton but just as concerning as the result was the injuries suffered by both Reece James and Andreas Christensen.
James was withdrawn with a hamstring problem, while Christensen has hurt his back.
Timo Werner and Ben Chilwell were already missing, with the latter set to undergo surgery on his anterior cruciate ligament.
Thiago Silva missed the Brighton game due to a thigh problem, but that seems to have been a precautionary measure rather than due to the severity of an injury, so the influential Brazilian may be passed fit for such a crucial game against Liverpool.
Edouard Mendy will start in goal in behind a likely back four or Trevoh Chalobah, Thiago Silva and Antonio Rudiger.
With James missing, that should see Azpilicueta move into the right wing-back role in place of Chrisian Pulisic, who might drop to the bench.
Marcos Alonso is the only real option on the left, while N'Golo Kante and Jorginho should start in midfield.
This week Romelu Lukaku gave an astonishing interview in which he criticised the tactics of Tuchel before indicating a desire to return to Inter. Normally, in this situation a player may be exiled by the manager, but it is up to Tuchel as to whether he wants his record signing in place for this important match.
To convey harmony, Tuchel might throw him in.
Kai Havertz and Mason Mount could be the players to complete the front three.
Liverpool are in a much healthier condition than Chelsea when it comes to injuries, as they only have Nat Phillips, Adrian, Divock Origi and Harvey Elliott unavailable.
Alisson will start in goal behind a back four of Trent Alexander-Arnold, Joel Matip, Virgil van Dijk and Kostas Tsimikas. Andy Robertson is again unavailable due to a suspension.
Thiago might be back involved for the Reds after missing training this week following a positive Covid test, but he will likely be on the bench at the start which will see Fabinho, Jordan Henderson and Alex Oxlade-Chamberlain continue in midfield.
Liverpool lost 1-0 in their last game against Leicester, but Jurgen Klopp will probably keep faith in Mohamed Salah, Diogo Jota and Sadio Mane up top.