Arsenal coach Mikel Arteta needs to pick his side up after their Europa League semi final defeat to Villarreal in midweek.
The Gunners failed to score at The Emirates on Thursday evening against the Spanish side, and the goalless draw was enough to secure a final berth for Unai Emery's side.
The exit means their season is all-but over with four games remaining, with no chance of the club making it into the Champions League next season.
However in spite of this, Arteta will want a strong performance from his side, and therefore will likely name his best side in order to secure victory against The Baggies.
Mat Ryan could start in goal at the expense of Bernd Leno, however, and Calum Chambers should return to the defence at right-back, with Hector Bellerin dropping to the bench.
Pablo Mari and Rob Holding will retain their places at the heart of the defence, as will left-back Kieran Tierney.
Granit Xhaka is a doubt after pulling out just before the game against Villarreal with muscle tightness, but Arteta is hopeful that the midfielder will be able to play from the off.
Thomas Partey, who is still struggling to adapt to English football, will also keep his place in midfield.
Bukayo Saka, Emile Smith Rowe and Gabriel Martinelli are all likely to start against West Brom, Nicolas Pepe and Martin Odegaard will drop to the bench.
Pierre-Emerick Aubameyang will lead the line for Arsenal, despite only scoring 15 goals this season.