Antonio Conte’s side presently reside in second, just one point behind their great rivals, having strung together an impressive six game-winning sequence.
The latest of these triumphs came against Spezia at San Siro on Sunday, with goals from Achraf Hamkimi and the in-form Romelu Lukaku getting the Nerazzurri over the line in a 2-1 win.
This encounter will be Inter’s last before a brief recess for Christmas. They will have around 10 days before their next encounter against Crotone, and they will be going all-out to finish the year on a high note.
Conte should have a strong squad open to him. There were doubts over the fitness of Marcelo Brozovic and Arturo Vidal prior to the weekend’s match, but both played a role, indicating that they are available for action.
Meanwhile, the coach took precautions to rest the likes of Ashley Young, Hakimi and Lukaku by withdrawing them early from the Spezia clash, which would hint that they are set to receive starts on Wednesday.
On the injury front, there are still some issues. The most pressing of these is to attacker Alexis Sanchez, who continues to miss out after scoring a couple of times this season. Offensive cohort Andrea Pinamonti is also laid up. In midfield, Radja Nainggolan is absent along with Matias Vecino, who has yet to play this season.
The prospect of Conte making significant changes to his line up seems unlikely. He has enjoyed a settled team throughout this winning run and is unlikely to greatly tamper with it.
If Vidal is fit enough, he could come into the midfielder to replace Nicolo Barella while Ivan Perisic is a candidate to replace Young on the left, although that would go against the substitution he made at the weekend.
Meanwhile, this could be Christian Eriksen's last appearance for the club.