Roberto Firmino usually plays in the position and could make a comeback for this game, pending a late fitness test on a knee injury that has kept him out of the last two matches.
But even if Firmino is passed fit to play, Jota may still keep the spot as has performed well in the absence of the Brazil international, who could be eased back via a place on the bench.
Jota should be partnered by Mohamed Salah and Sadio Mane in attack.
An impressive 4-0 aggregate win over RB Leipzig in the Champions League has come as a boost, but they have slumped down to eighth in the top-flight table.
Fabinho’s influence returning to midfield in the second leg against Leipzig on Wednesday has been praised.
There is a strong chance Klopp keeps an unchanged team, meaning Georginio Wijnaldum and Thiago Alcantara also start in midfield.
Ozan Kabak and Nat Phillips make up an inexperienced centre-back pairing, but one which kept Leipzig at bay and allowed Fabinho to play further up the pitch.
Established first-teamers Alisson, Trent Alexander-Arnold and Andy Robertson make up the other spots in our predicted XI.
Jota had an assist against Leipzig, which was only his second start since early December, having had a lengthy injury absence.
Crucial quartet Virgil van Dijk, Joel Matip, Joe Gomez and Jordan Henderson are all still out for Liverpool.