Former Newcastle and Chelsea forward Demba Ba was the man on the spot to down Manchester United, firing his Istanbul Basaksehir side to a 2-1 victory in the Champions League.
United were off the pace from the start and some utterly bizarre and naive defending allowed the 35-year-old to finish with conviction for the opening goal.
And it got worse five minutes before half-time, Visca taking advantage of an intelligent step-over from Ba to steady himself and smash into the net past Dean Henderson, who was deputising for David de Gea.
United hit back when Luke Shaw swung a cross in and Anthony Martial headed home, and in the second half they utterly dominated the ball.
But they could not find a way to create any clear cut chances and managed just three shots on target despite completing more than double the passes of the Turkish side.
United's best open came in injury time when Epureanu somehow managed to hook a botched clearance off the goal line, but it would have been an undeserved point for a lacklustre United display which only garnered a 6.3 FC Rating.
Manchester United are still in a good position in the group having won their first two matches, but this result will not sit well with United fans and the trip to Goodison Park on Saturday now looks like a pivotal match.