He was back training with the team during the week, though, and is in line for his first start under Tuchel since the German replaced Frank Lampard as boss.
Kepa Arrizabalaga started in the last round against Luton and will probably do so again, while Marcos Alonso could return at left-back.
Tuchel has utilised a back three since taking over, but could revert to a back four in a game that Chelsea are expected to win. This has also been impacted by the injury suffered by Thiago Silva.
Reece James and Andreas Christensen could retain their places from the weekend, with Kurt Zouma coming in for Antonio Rudiger.
In midfield, Billy Gilmour will be given a run out, potentially partnered by N'Golo Kante which keams Jorginho and Mateo Kovacic dropping to the bench.
Timo Werner suffered a dead leg on Sunday, and although he is fine now, expect him to be rested.