The Champions League has been a rare source of positivity for the Blaugrana this season, as they opened up their account with a big win over Ferencvaros before impressively sweeping aside Juventus at the Allianz Stadium at week ago.
Their European form is in contrast to their performances in La Liga, as they dropped points at the weekend again, this time drawing 1-1 away at Alaves.
Neto was at fault for the conceded goal, and although Marc-Andre ter Stegen is back in the squad for this game, the Brazilian will likely continue in goa until the weekend.
Barca are also boosted by the return of Gerard Pique, who will partner Clement Lenglet in the middle of the defence after missing the Juve game due to suspension.
Sergio Busquets and Frenkie de Jong will probably start in the middle of midfield even though the Spaniard was withdrawn against Alaves after failing to impress.
Ousmane Dembele will likely not be as fortunate, with Pedri in line to take his place on the right. The Frenchman was given a started against Alaves but, like Busquets, was taken off at half-time.
Should Koeman decide against Busquets, it'll mean a start for Miralem Pjanic.
Samuel Umtiti, Philippe Coutinho and Ronald Araujo are all injured.