The French champions successfully defeated Basaksehir 2-0 thanks to two goals from Moise Kean during the week, but the victory was soured by the news that Neymar is set to miss the next few matches due to an abductor injury.
The Brazilian lasted just 26 minutes in the game before he was replaced by Pablo Sarabia.
As things stand, he is set to miss games against Nantes. RB Leipzig, and Rennes.
Angel Di Maria is serving the final match of his four-game suspension, which could mean a start for Sarabia after he replaced Neymar on Tuesday.
Julian Draxler, Marco Verratti, Mauro Icardi, Leandro Paredes, and Juan Bernat are all on the injured list.
But, Idrissa Gueye is in contention to start after he made his return from injury against the Turkish side.
In the absence of Neymar, the attacking impetus will be on Kylian Mbappe, who could be asked to play in a wider role if Moise Kean is given a start.
The Italian was the match winner in the Champions League, scoring two goals, and has earned a place in the starting XI.