The two sides face off in the Premier League in entirely different circumstances, as Tottenham look to keep their spot at the top of the table and Arsenal hope to pull themselves up from the depths of 14th place.
In order to do that, Mourinho’s side will almost certainly need Kane leading the line at the Tottenham Hotspur Stadium on Sunday.
And the Spurs manager is confident that he’ll be able to call upon his striker’s talents.
"I believe [Harry Kane] is going to be fit,” said Mourinho after Thursday’s night 3-3 Europa League draw with LASK, which Kane missed through injury.
“I'm not sure. He's having treatment but I could be doing some bluff and pretend he's in trouble, but he's not and I think he'll play [against Arsenal]."
"I don't want to lie, I don't want to hide anything in relation to is he going to play or not? I think he's going to play. That's my feeling is that he's going to play."
The England striker has been in fantastic form this season, with 13 goals and 11 assists in just 16 games for Tottenham.
Although Kane did play the full 90 minutes in last weekend’s 0-0 draw with Chelsea, Mourinho confirmed the striker would miss the midweek clash with their Austrian foe without going into specifics about Kane’s injury.