Dortmund go into this week's Champions League clash against Club Brugge with only one fit central defender, which will force Lucien Favre to further tinker with his line-up.
Mats Hummels was the two-goal hero for BVB in the weekend win over Arminia, but had to be withdrawn due to a thigh injury a few minutes from time.
With Emre Can, Dan-Axel Zagadou, Marcel Schmelzer and Nico Schulz all out injured, too, that leaves Favre without many options at the back.
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Manuel Akanji is the only fit central defender, which means 35-year-old Lukasx Piszczek could be asked to play in a back four, with Thomas Meunier and Raphael Guerreiro in the full-back roles.
Jude Bellingham will likely start after playing well against Arminia, with either Thomas Delaney or Axel Witsel partnering the young Englishman in central midfield.
It was a rare game missed for Erling Haaland at the weekend but he is available for Champions League duty, which might mean a place on the bench for Thorgan Hazard.
If Marco Reus moves out to the left, Haaland can take his place up top.