Both teams currently sit level on points at the top of the Bundesliga table, with five wins and a single loss each after six games.
And with key players returning for both teams, it will almost certainly be a clash that could fall in favour for either side.
Lucien Favre will be boosted by the prospects of star central defender Mats Hummels returning to action ahead of Saturday’s clash.
The 31-year old missed Dortmund’s midweek Champions League win over Club Brugge after picking up a hamstring injury against Arminia Bielefeld last weekend, yet it seems as though Hummels should be fit and ready to return to action after taking the week off.
The senior defender also joins Erling Haaland, who missed the previous matchday’s win over Bielefeld with a knee injury, only to return in time for the win over Brugge.
Similarly, Hans-Dieter Flick will be hoping to welcome back one of his own star players in midfield maestro Leon Goretzka.
The former Schalke player returned to training this week, following a calf injury that had ruled him out of last weekend’s win over Koln and the midweek European tie victory over RB Salzburg.
Whether the midfielder gets to start on Saturday is another question entirely, but Flick will be happy to have the box-to-box midfielder back on the bench at the very least.
Elsewhere, Bayern will also be pleased to see their talismanic centre-forward Robert Lewandowski start on Saturday after returning from a rest last weekend to score two goals on Tuesday against Salzburg.
Niklas Sule, who tested positive for coronavirus at the start of the week, will miss the tie as he continues his quarantine.