The Frenchman tested positive for coronavirus while on international duty with the French U21s side, and has been subsequently quarantined.
However, enough time has passed that he has returned to training, and although fitness may be a slight issue, it is too big a match for Neil Lennon not to take a gamble on his star man.
The virus has impacted Celtic in other areas, too, with Hatem Abd Elhamed, Nir Bitton and Ryan Christie all currently isolating after receiving a positive test or coming in contact with someone who has.
Some better news for the Hoops should be the return of Albian Ajeti, though, after the West Ham loanee missed the last two games through injury.
After being given an extremely rare rest from the starting XI against St. Johnstone, Scott Brown will be reinstated into the line-up for the fierce midfield battle.
Greg Taylor will probably be given the nod at left wingback ahead of new signing Diego Laxalt.
There are continued worries about the fitness of Allan McGregor, central defender Filip Helander, midfielder Joe Aribo and centre-forward Kemar Roofe.
It is likely that Jon McLaughlin will continue in goal, while Leon Balogun could play instead of Helander.
Should Steven Gerrard opt for a more attacking line-up, Ryan Kent and Ianis Hagi will partner Morelos in attack, with Steven Davis, Glen Kamara, and Scott Arfield in midfield.