BVB secured wins against Schalke and then Wolfsburg on Saturday, while Bayern defeated Union Berlin before destroying Eintracht Frankfurt 5-2.
The two championship candidates are playing some scintillating football, and with just four points separating them in the table, BVB could shrink the gap to a solitary point if they can emerge victorious in Der Klassiker.
Bayern, though, could move seven points clear, which would represent perhaps the most vital moment of the championship race so far in 19/20.
Dortmund have scored six goals in two games and, perhaps more tellingly, have conceded none in the two fixtures. If BVB have managed to sort their leaky defence which continually cost them points in the first half of the season, then Bayern should be worried.
Lucien Favre's men followed up their magical performance against Schalke with a much more reserved outing versus Wolfsburg, as although they controlled the game for the most part with 61% possession, they only sent six shots on goals, actually being outperformed by Wolfsburg in that regard.
It was a game of dominance, though, as they completed 594 passes to Wolfsburg's 336, and made 11 more interceptions (16-5).
In contrast to Dortmund, Bayern were reserved in their first game back last weekend before going gung-ho in attack this weekend, firing five goals past Eintracht Frankfurt at an empty Allianz Arena on Saturday.
Leon Goretzka, Thomas Muller, Robert Lewandowski, and Alphonso Davies all scored for the defending champions, with Martin Hinteregger scoring an own goal for the visitors.
Davies once again impressed for Bayern, recording an assist as well as his goal, and earned the rating for the best performer in the match with a score of 8.3.
Marco Reus, Nico Schulz and Dan-Axel Zagadou remain definite absentees for Dortmund, but more worryingly they face a race against time to get Mats Hummels fit, with the big defender leaving the pitch against Wolfsburg due to an Achilles injury at the weekend.
Axel Witsel remains a doubt, but Emre Can and Jadon Sancho could be fit enough to start the game after both coming on as substitutes on Saturday.
Hansi Flick decided to rest Serge Gnabry against Eintracht, with Ivan Perisic given a start, but expect the German international to return to the starting XI here at the expense of his Croatian team-mate.
Phillipe Coutinho and Corentin Tolisso are still shelved with ankle issues, while Niklas Sule and Thiago are not expected to feature.
LIKELY STARTING XIs
Dortmund (3-4-3): Burki; Piszczek, Hummels, Akanji; Hakimi, Can, Brandt, Guerreiro; Sancho, Haaland, Hazard
Bayern (4-2-3-1): Neuer; Pavard, Boateng, Alaba, Davies; Kimmich, Goretzka; Gnabry, Muller, Coman; Lewandowski
PLAYER TO WATCH
Flick took the opportunity to rest Gnabry at the weekend, and although he was given game time for the last third of the game against Eintracht, he will be raring to go when he returns to the starting line-up in Der Klassiker.
He has contributed to 20 goals (11 goals, nine assists) in the Bundesliga for the defending champions this season, and promises to be involved in one of the battles of the game on Tuesday as he goes up against Achraf Hakimi.