Bale completed a return to his former club in the summer on loan from Real Madrid, but due to injury he is yet to debut in the 2020/21 season in his second stint with the London side.
Jose Mourinho confirmed this week that the Welshman is available for selection against the Hammers.
However, it is likely from the bench that we'll see him make his first appearance of the season, with Mourinho probably keen to keep the attacking momentum going following the massive 6-1 away victory against Man Utd before the international break.
Where possible, the Portuguese boss will name pretty much the same XI that embarrassed United a couple of weeks ago.
The only alteration from that line-up could be the absence of Eric Dier, who picked up a hamstring injury while on international duty with England.
That could mean Toby Alderweireld partnering Davinson Sanchez in the middle of the defence.
Giovani Lo Celso and Japhet Tanganga remain absent.