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Ruben Amorim has taken charge of two Manchester United games so far but this is his first at home in the Premier League
Aston Villa will be hoping to end a poor run of form when they travel to Stamford Bridge on Sunday
Both West Ham and Arsenal are coming off excellent victories so this should be an entertaining one at the London Stadium
Wolves will look to continue their positive form this weekend when they host Wolves at Molineux
Ruben Amorim has taken charge of two Manchester United games so far but this is his first at home in the Premier League
Aston Villa are without a win in seven matches across all competitions and face a tough visit to Chelsea on Sunday
Paris Saint-Germain have again been dominant in Ligue 1, but have struggled for form in the Champions League
Barcelona are without a win in two matches in La Liga and it has opened the title race right up
Milan are on an unbeaten run of five matches across all competitions and are favoured to make it six at home to Empoli
The first Klassiker of the season takes place this weekend as Bayern Munich travel to face Borussia Dortmund
Arsenal put in one of their best performances of the season midweek against Sporting CP in the Champions League
Wolves are on an uncharacteristic decent run at the moment but face a Bournemouth side that have recently beat Arsenal and Man City
Chelsea are blowing away teams in the Europa Conference League and remain big favourites for this one away at Heidenheim
Ajax are unbeaten in 16 matches in all competitions but face a tough task in Spain as they take on Real Sociedad
It has been a season to forget so far for Rangers and they face a tough away test in the Europa League on Thursday versus Nice
Tottenham's confidence will be soaring at the moment following their 4-0 away win against Man City on Saturday, and on Thursday face Italian giants Roma
Celtic have won both their home matches in the Champions League this season but need to be wary of a dangerous Club Brugge side
Unbeaten Inter are going for three matches won in a row in the Champions League, while RB Leipzig must recover from a loss versus Celtic
Arsenal face a tough task away at Sporting CP this week as the Portuguese giants have already claimed the scalp on Man City in the Champions League
Pep Guardiola is hoping to stop the rot at Manchester City as his team have now loss five games in a row following the Tottenham defeat
Two of Europe's elite sides face off in the Champions League on Tuesday as Bayern Munich host Paris Saint-Germain
Celtic have won both home Champions League matches in the League Phase so far, but face a tough task against Club Brugge
Sporting CP take on Arsenal this Tuesday in what is their first Champions League fixture since Ruben Amorim departed for Man Utd
Manchester City have lost five matches in a row for the first time since the days of Stuart Pearce but will still fancy themselves against Feyenoord
Two of Europe's big guns go head-to-head in the Champions League on Tuesday, as Bayern Munich host Paris Saint-Germain